Tuesday, May 7, 2019

Over-the-counter drugs and amphetamines

Amphetamine is a group of synthetic psychoactive drugs called central nervous system [CNS] stimulants. Amphetamine-containing drugs are used for narcolepsy, obesity, and attention deficit hyperactivity disorder.

When benzylamine was first synthesized by the German chemist L. Edeleano in 1887, no stimulating effects were noted. In the early 1930s, when amphetamine-type central nervous system stimulant properties and use as a respiratory stimulant were discovered, it was marketed as an inhaler for nasal congestion [Benzeredrine©]. Benzedrine is the trade name for the drug amphetamine; dextroamphetamine is marketed as Dexedrine. Methamphetamine is a potent stimulant sold by Desoxyn and is the fastest-acting amphetamine. This inhaler is now banned for its toxicity, but it can still be used for a limited use.

Amphetamine may have acute systemic effects, including heart irregularities and stomach problems. Chronic use often leads to insomnia, hyperactivity, irritability and aggressive behavior.

In the 1960s and 1970s, the abuse of amphetamine began to rise, and it was found that intravenous injection of amphetamine [especially methamphetamine] produced an enhanced euphoric effect that was faster than oral administration. Amphetamines are also very popular among athletes during training, as athletes' performance has improved as cardiac output has increased.

Often referred to as bennies, cranks, speeds, pep pills, wakes or uppers, amphetamines are highly addictive and abusive. Users risk being psychologically dependent on drugs and are resistant to them. This has led to the need for larger and larger doses to achieve the same effect.

Addiction may die from mental disorders or excessive exhaustion or sudden cardiac arrest. Amphetamine-induced psychosis has significant similarities with schizophrenia, with paranoia and hallucinations.

No known over-the-counter drugs contain amphetamine, although many of these drugs test false positives for amphetamines.





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