Mantle cell lymphoma is a subtype of B cell or B lymphocyte lymphoma classified in non-Hodgkin's lymphoma. This type of lymphoma is due to the malignant transformation of B cells. These B cells are part of the immune system and are responsible for destroying microorganisms that invade the body. The disease is named for its malignant B cells and is common in the coat of the lymph nodes. In morphological studies, this will manifest as a non-invasive type of lymphoma. However, mantle cell lymphoma is an invasive B-cell lymphoma that spreads rapidly in the body.
Mantle cell lymphoma is a rare non-Hodgkin's lymphoma. About 7% of patients in this category include age groups over 60 years of age. This type of lymphoma is diagnosed by a swollen, non-tender lymph node located in the throat and may involve other nodes, such as lymph nodes located near the clavicle, armpit, chest, and groin. Malignant cells can also metastasize in the spleen and liver, giving a feeling of a complete distributed abdomen. The fatigue in this case is due to anemia caused by the spleen, bone marrow involvement, and unexplained fever and weight loss. Symptoms of stomach problems such as nausea and vomiting can also be observed.
Treatment of mantle cell lymphoma is based on the current stage of malignancy and metastasis. Rituximab is used to help the immune system find malignant cells and destroy them with the help of interferons that act as immune system boosters. The combination of R-CHOP with rituximab and steroids is often used as a chemotherapy to destroy cancer cells. In Phase I and Phase II, treatment with topical radiation therapy with or without the aid of a chemotherapeutic agent. To help the body recover, stem cell therapy such as bone marrow transplantation is an active form of treatment when the disease is in advanced stages.
The method of treating mantle cell lymphoma is still being studied without causing too many side effects. The MCL Alliance is a group of doctors dedicated to fighting this disease. Their website provides researchers and patients with a set of cell lymphoma resources designed to help people understand the malignancy and bring patients and survivors together to form a support group.
Orignal From: What is mantle cell lymphoma?
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