Close relatives are marriages that occur between close relatives or cousins. According to a recent study published by the JAMA Psychiatry Journal, children born from the first generation of cousins can be seen. At some point in their lives, marriage is three to five times more likely to be treated with medications for mood disorders such as anxiety and depression. In addition, they are twice as likely to use antipsychotics to treat brain diseases such as schizophrenia.
Although the researchers did not determine why this risk exists, past studies have determined that these children are likely to develop monogenic diseases such as sickle cell disease, cystic fibrosis, fragile X syndrome, and Huntington's disease. Cognitive and learning disabilities. These conditions arise when the parents of these children inherit specific DNA from their common grandparents.
Lifelong schizophrenia, depression
The researchers surveyed 363,960 individuals born in Northern Ireland between 1971 and 1986 until 2014. After the child is born, his or her parents are asked how close they are to each other. Participants' mental health status was examined by analyzing their prescriptions for antipsychotics and anxiolytics and antidepressants between 2010 and 2014.
According to the study, nearly one in ten children have close parents or second generation cousins. On average, the lifetime risk of schizophrenia is between 0.3% and 0.66%, while for acquaintance children it is doubled. This means that these children are 99% more likely to need antipsychotics at some stage of their lives.
For most people, the risk of a lifetime of depression is 10%, but for cousins children, it is three times. This is equivalent to 70% of the likelihood that they have never had an antidepressant.
The authors add that even if there is no reproduction between relatives, single-gene disease may be paralyzed in isolated communities. According to them, the first cousin who wants to get married should receive expertise in genetic counseling and the risk factors involved.
Prior to this study, Leeds and Bradford University published a study in 2013 that showed that children of the first generation of cousins were prone to fatal congenital defects such as Down syndrome and cardiopulmonary problems. .
Mental health of close relatives and future generations
Since the Middle Ages, West Asia and North Africa, and immigrant communities from Europe, Australia and North America, close relatives have been practicing in practice. Past research has shown that close relatives marry a social disorder such as social phobia, generalized anxiety disorder, specific phobia, major depression, and personality disorder.
When parents move to different countries to pursue their dreams, the risk of such legitimate children is higher. Cultural differences and social unacceptability can affect a child's physical and mental health, making him or she feel displaced and isolated, resulting in a low sense of self-worth, a sense of despair and a lack of depression, depression.
Ways to improve mental health
Pre-marital and pre-pregnancy counseling must be provided to couples who are related to each other so that they fully understand the imminent risks. School and community-based programs should be provided for children to better assess mental health. The awareness program should also consider this part of society to distribute important information. Timely diagnosis can help protect the mental health of vulnerable groups.
Orignal From: Cousin-couples' Studies show that children are susceptible to serious psychological problems
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