Dapagliflozin [Farxiga] is a SGLT2 inhibitor that is administered in the form of pills to people who have been diagnosed with type 2 diabetes and who are used with diet and exercise, and sometimes with other drugs. Its role is to let the kidneys secrete more sugar in the urine. According to a study published in the magazine in October 2018 from
Cardiovascular diabetes, from
The drug also helps treat a complication of type 2 diabetes - heart failure.
When heart failure occurs on the left side of the heart It is impossible to absorb blood from the lungs and transport it quickly to other parts of the body.
The heart is made up of muscle tissue that grows when stressed. This muscle ingrowth allows a smaller space to accommodate blood flow from the lungs. This causes heart failure and fills the lungs with fluid in the blood.
In 2017, an estimated 26 million people worldwide suffered from heart failure. In type 2 diabetes, high blood sugar levels can damage the heart and blood vessels and can cause high blood pressure. It is important to reduce blood pressure readings to a healthy level to reduce heart pressure. A heart attack may not cause chest pain in patients with type 2 diabetes, resulting in reduced nerve damage. This makes it more urgent to prevent heart disease.
Investigators at Kobe University and several other research institutions in Japan studied 58 people with type 2 diabetes and heart failure. Dapagliflozin was added to its conventional regimen at a dose of 5 mg / day. After six months, the size of the muscle tissue on the left side of the heart following the diabetic patient decreased. Brain natriuretic peptide [BNP] is a protein secreted by heart cells that is reduced in participants with very high BNP for overstretching. Based on this information, the researchers concluded that dapagliflozin may help improve heart failure in patients with type 2 diabetes.
The natriuretic peptide effectively causes the kidney to secretly enter potassium into the kidney, lowering blood pressure and the amount of blood in the heart and blood vessels.
Dapagliflozin is given once a day, with or without food. It is defined as part of a holistic treatment plan that includes diet and exercise. Side effects include...
- Urinary tract yeast infection,
- a sore throat,
- Often urinating in large quantities and at night,
- Dizziness or dizziness,
- Ketoacidosis [checking ketones in urine]
- Nausea and vomiting,
- feeling very tired,
- Difficulty breathing,
- Abdominal pain, and
- Kidney damage.
Orignal From: Type 2 diabetes - an oral medication that prevents heart failure and lowers blood sugar
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